发育健康营养多组学大数据领域发表论文46篇，其中通讯或第一作者22篇，参与10篇顶尖期刊(The Lancet, Nature )论文；6个特邀报告。 代谢组NMR分析与药物毒理研究.波谱学杂志, 2011, 28 (1), 1-17. 1st & Correspondence. Dynamic metabolic response of mice to acute mequindox exposure. Journal of Proteome Research, 2011, 10, 5183-5190. 1st. Systems responses of rats to mequindox revealed by metabolic and transcriptomic profiling. Journal of Proteome Research, 2012, 11, 4712-4721. 1st. ECR-MAPK regulation in liver early development. BioMed Research International,2014: 850802. 1st & Correspondence. Intervention of pumpkin seed oil on metabolic disease revealed by metabonomics and transcript profile. Journal of the Science of Food and Agriculture, 2017, 97(4): 1158-1163. 1st & Correspondence. Dynamic Lipid Profile of Hyperlipidemia Mice. Journal of Chromatography B, 2017, 1055–1056: 165–171. Correspondence. Risk Factors and Biomarkers of Non-alcoholic Fatty Liver Disease: an observational cross-sectional population survey. BMJ open. 2018;8:e019974. Correspondence. 以中国中部地区1479人横断面观察型临床试验为对象，运用代谢组检测、多变量Logistic回归和接受者操作特征曲线下面积（AUROC），发现非酒精性脂肪肝病（NAFLD）新的高发年龄段50-60岁和新的危险因素与生物标志物油酸羟化油酸酯。 Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet 2018; 392: 1995–2051. Coauthor. Prediction of cause-specific disability-adjusted life-years in China 2018-2021: a systematic analysis. Public Health. 2020,180:90-99. Correspondence. Global, regional, and national burden of cirrhosis by aetiology in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017.The Lancet Gastroenterology & Hepatology 2020;5(3):245-266. Coauthor. NMR-based plasma metabonomics in Hyperlipidemia Mice. Analytical Methods 2020, 12, 1995 - 2001. Correspondence. Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017. Nature Medicine 2020, 26: 750–759. coauthor Mapping geographic inequalities in childhood diarrhoeal morbidity and mortality in low- and middle-income countries, 2000–17: analysis for the Global Burden of Disease Study 2017. The Lancet 2020, 395(10239)：1779-1801. Coauthor. Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17. The Lancet Global Health 2020, 8(8):e1038-e1060. Coauthor. Measuring universal health coverage using the UHC effective coverage index in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019. The Lancet DOI: 10.1016/S0140-6736(20)30750-9. Coauthor. Global burden of 302 diseases, injuries, and impairments, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet Coauthor. The unfulfilled promise of prevention: the global burden of 86 risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet Coauthor. Five insights from the Global Burden of Disease Study 2019. The Lancet Coauthor. Prediction of cause-specific disability-adjusted life-years in China 2018-2021: a systematic analysis. Public Health 2020,180:90-99. Intervention of 4% salmon phospholipid on metabolic syndrome in mice based on colonic lipidomics analysis. Journal of the Science of Food and Agriculture, 102 (8), 3088-3098 (2022). Linking research of biomedical datasets. Briefings in Bioinformatics 2022, 23 (6): bbac373. DOI: 10.1093/bib/bbac373. Review. 数学与计算生物学 1/57。1st & Correspondence. 提出生物数据学（biodatatics），概括其类脑生态理论，即全流程数据活动机制DCSAE（多样兼顾，环节衔接，安全共享，权责一致，生态使能）多样化弱关联数据集通过原生类脑方式（动力引擎和思想知识双轮驱动，算法和算力协调匹配）预测发现。数据环节，概括为设计、采样、预处理与分析和治理，通过技术导则、标准化、应用程序接口、软件开发包、模型参数等衔接。匿名化和去标识化，对抗训练，群体学习，高性能图计算，图查询语言，混合事务分析处理等，兼顾深度计算、海量存储和高并发通讯，实现数据安全共享。以比例原则分配不同数据参与方的权利与义务、权力与职责。数据在使用中升值，不同数据参与方都能从中获益，形成数据生态系统（物料平衡、能量守恒、简单优先）。 Dietary interventions of salmon and silver carp phospholipids on mice with metabolic syndrome based on lipidomics. Cells, 2022, 11, 3199. |
