韩笛 讲师
电 话：13667286551 |
邮 箱:13667286551@163.com |
毕业院校：武汉大学 |
政治面貌：中共党员 |
教育经历
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2018.9-2023.6 |
武汉大学 |
高分子化学与物理专业 |
博士 |
2014.9 -2018.6 |
武汉工程大学 |
应用化学专业 |
学士 |
研究领域
主要开发天然功能化的药物和核酸传递系统用于疾病诊断和治疗，以实现诊疗一体化。包括：
1. 天然功能化的核酸传递系统在疾病诊断中的研究；
2. 天然功能化的药物和核酸传递系统在疾病治疗中的研究；
3. 诊疗一体化新材料的开发。
代表性成果：
1. Di Han, Xiao-Yan He, Min Gao, Xiao-He Ren, Xin-Ru Liao, Xue-Si Chen, Xuan Pang, Si-Xue Cheng*, A Multifunctional Delivery System for Remodulating Cell Behaviors of Circulating Malignant Cells to Prevent Cell Fusion. Adv. Sci., 2023, 10, 2303309.
2. Di Han, Xiao-He Ren, Xin-Ru Liao, Xiao-Yan He*, Tao Guo*, Xue-Si Chen, Xuan Pang, Si-Xue Cheng*，A multiple targeting nanoprobe for identifying cancer metastatic sites based on detection of various mrnas in circulating tumor cells. Nano Lett., 2023, 23, 3678-3686.
3. Di Han, Chang Xu, Xiao-He Ren, Yan Peng, Bin Xu, Jun-Long Song, Jing Chen, and Si-Xue Cheng*, In situ detection of nanotoxicity in living cells based on multiple miRNAs probed by a peptide functionalized nanoprobe. Anal. Chem., 2022, 94, 2399-2407.
4. Di Han, Xiao-He Ren, Xiao-Yan He, Xue-Si Chen, Xuan Pang, Si-Xue Cheng*, Aptamer/Peptide-Functionalized Nanoprobe for Detecting Multiple miRNAs in Circulating Malignant Cells to Study Tumor Heterogeneity. ACS Biomater. Sci. Eng., 2023, 9, 5832-5842.
5. Si-Xue Cheng, Di Han, Molecular beacon based nanoprobes for directly detecting organ-specific matastasis related biomarkers of tumor cells in peripheral blood, preparation method and application: US 18/105,233[P]. 2023-02-02. (专利，导师排第一，本人排第二)
6. 程巳雪, 韩笛. 直接检测外周血中肿瘤细胞器官特异性转移相关基因的分子信标纳米探针及其制备方法及应用: CN202210314411.2[P]. 2022-03-28. (专利，导师排第一，本人排第二)
